MCAM anticorps
Aperçu rapide pour MCAM anticorps (ABIN7268460)
Antigène
Voir toutes MCAM AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- CD146/MCAM Rabbit mAb
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- A synthesized peptide derived from human CD146/MCAM
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- MCAM (Melanoma Cell Adhesion Molecule (MCAM))
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Autre désignation
- MCAM
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Sujet
- Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.,CD146, MUC18,Cancer,CDs,Cell Adhesion,Cell Adhesion_Cell Adhesion Molecules,Cell Biology & Developmental Biology,Cytoskeleton,Endothelial Progenitors,Immunology & Inflammation,Invasion and Metastasis,Signal Transduction,Stem Cells,MCAM
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Poids moléculaire
- 72kDa
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ID gène
- 4162
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UniProt
- P43121
Antigène
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